mithridatism

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition

  • noun Tolerance or immunity to a poison acquired by taking gradually larger doses of it.

from The Century Dictionary and Cyclopedia

  • noun Immunity against the action of a poison acquired by taking the drug in constantly increasing doses: a method said to have been conceived by Mithridates to protect himself against palace intrigues.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • noun The development of immunity to a poison by gradual ingestion of successively greater amounts.

Examples

  • It's hard not to think of Iocane powder; but arsenic is a classic real example of a poison where mithridatism is possible, as with the (possibly exaggerated) Arsenic Eaters of Styria, 19th century Austrian peasants who habitually ate, as a tonic, normally lethal doses of arsenic.

    Arsenic

  • This is the case of (relative) immunization or, as it is sometimes called, of mithridatism.

    Charles Richet - Nobel Lecture

Note

The word 'mithridatism' comes from the name of Mithridates VI of Pontus.