Hsp70

Previous studies in cell culture and animal models of neurodegenerative disease found that increasing the amount of available protein chaperones, such as Hsp70 and Hsp40, can suppress protein aggregation and prevent polyQ disease-related damage to neurons.

PLoS Biology: New Articles 2010

Experiments in cell and animal models of neurodegenerative disease demonstrate that increased levels of individual protein chaperones such as Hsp70, Hsp40, or Hsp27 can significantly suppress protein aggregation, increase protein solubility and turnover, and ameliorate neuronal loss

PLoS Biology: New Articles Daniel W. Neef et al. 2010

Since the resulting increase in intracellular ionic strength is harmful for the function of cellular components, cells synthesize chaperones, such as Hsp70, as well as enzymes and transporters whose collective function is to increase the intracellular concentration of compatible organic osmolytes to normalize the ionic strength of the intracellular fluid

PLoS ONE Alerts: New Articles Katherine Drews-Elger et al. 2009

I compared the abundance levels back in days for the TAP-MS data and despite the fact that many of the contaminants are highly abundant proteins such Eno1 and the Hsp70 chaperones, failed to observe a positive correlation between interaction number and abundance.

Public Rambling Pedro Beltrao 2006

Petesch SJ, Lis JT (2008) Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci.

PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70.

SpaceRef Top Stories 2010

Wegrzyn RD, Chernova TA, Muller S, Newnam GP, et al. (2005) Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the

PLoS ONE Alerts: New Articles Marc Erhardt et al. 2010

This implies that genetic variants of Hsp70 genes such as

PLoS ONE Alerts: New Articles Meian He et al. 2010

Petesch SJ, Lis JT (2008) Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci.

PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

Petesch SJ, Lis JT (2008) Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci.

PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010