anoikis

Acquisition of resistance to "anoikis" facilitates the survival of cells under independent matrix-deficient conditions, such as cells in tumor progression and the production of suspension culture cells for biomedical engineering.

BioMed Central - Latest articles 2010

Moreover, the disruption of the interaction between epithelial cells and extracellular matrix ( 'anoikis') may play an important role in the onset of apoptosis in detached enterocytes

PLoS ONE Alerts: New Articles Joep P. M. Derikx et al. 2008

Apoptosis of detaching enterocytes after intestinal IR is potentially caused by loss of contact between the epithelial cells and extracellular matrix, and between neighbouring epithelial cells ( 'anoikis') [20], [31], [34].

PLoS ONE Alerts: New Articles Joep P. M. Derikx et al. 2008

There's a Greek term we use, anoikis, that means homeless -- humans have evolved so that healthy cells would rather be dead than in the wrong home.

Leading the Hunt For Cancer Genes 2007

Cells that detach from their environment undergo a form of programmed cell death called anoikis.

blueollie blueollie 2010

The stress hormone treatment activated a protein called FAK (focal adhesion kinase), which is known to protect cells from anoikis.

blueollie blueollie 2010

Detjen K, Welzel M, von MZ, Murphy D, et al. (2000) A novel function for the tumor suppressor p16 (INK4a): induction of anoikis via upregulation of the alpha (5) beta (1) fibronectin receptor.

PLoS ONE Alerts: New Articles Nadine Rohwer et al. 2010

"But cancer cells have come up with way to bypass this effect-they avoid anoikis," Sood says.

blueollie blueollie 2010

Welzel M, Daskalow K, Pfander D, Wiedenmann B, et al. (2008) Hypoxia-inducible factor 1alpha mediates anoikis resistance via suppression of alpha5 integrin.

PLoS ONE Alerts: New Articles Nadine Rohwer et al. 2010

Sood and his team first studied the effects of stress hormones on human ovarian cancer cell anoikis in culture.

blueollie blueollie 2010