atherogenicity

We know these folks know about LDL-cholesterol particle size and atherogenicity because they just described it.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

“We know these folks know about LDL-cholesterol particle size and atherogenicity because they just described it.”

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

Although there was some evidence for a reduction compared with baseline, apoB levels did not change significantly by week 24 in either group, suggesting that atherogenicity did not change despite a high or low saturated fat intake and the absence of an expected reduction in LDL-C with weight loss in the VLCHF.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

OTOH what you and others say is that the apoB number needs to be viewed with respect to any change in LDL as a rough marker of any changes in LDL particle size – and it is the result of this calculation which presents a more compelling marker as to changes in atherogenicity.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

And one would assume that since these reviewers were cardiologists – almost all of whom are lipid-hypothesis moths of the deepest dye – they would be up on apoB and LDL-particle size and the putative atherogenicity of small, dense LDL-cholesterol particles.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

The triglyceride-lowering effect of a low-carbohydrate diet leads to an increase in LDL particle size, which is known to decrease LDL atherogenicity.

Low-carb diet wins, losers cry foul | The Blog of Michael R. Eades, M.D. 2007

As apoB didn’t change significantly on either diet they then say that atherogenicity didn’t change either.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008

Did they actually say in the paper that particle size didn’t change, or do we have to infer that’s their conclusion from their atherogenicity language.

Low-carbs and lipids | The Blog of Michael R. Eades, M.D. 2008