Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
fibrous protein that forms apolyhedral coat on the surface of the coated pits and vesicles ofcells duringendocytosis
Etymologies
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Examples
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The vesicles also appeared to include a coat made from a molecule called clathrin, which helps form the outer shell of the vesicles.
Scientific Blogging 2008
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Interestingly, swiggle-mediated inhibition of MT1-MMP clathrin-mediated internalisation was also found to promote MT1-MMP-mediated cell migration.
BioMed Central - Latest articles Rochana Wickramasinghe 2010
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Since transferrin (Tf) is internalized mainly via clathrin-dependent endocytosis, we tested whether the extent of Tf uptake was affected upon treatment of HeLa cells with StxB.
PLoS ONE Alerts: New Articles Audrun Utskarpen et al. 2010
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Electron microscopy was used to quantify the number of clathrin-coated pits per mm of plasma membrane before and after incubating cells with Stx for 10 min at 37°C.
PLoS ONE Alerts: New Articles Audrun Utskarpen et al. 2010
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This anterograde transport is usually counterbalanced by the retrograde transport of membranes from the plasma membrane to endosomes and the Golgi apparatus via AP-clathrin-coated vesicles, and from the Golgi apparatus back to the ER via COPI-coated vesicles.
PLoS ONE Alerts: New Articles Michaela Norum et al. 2010
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Chen Y, Deng L, Maeno-Hikichi Y, Lai M, Chang S, et al. (2003) Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis.
PLoS Biology: New Articles Ting-Ting Hong et al. 2010
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MMP-2 active form then interact with the integrine αvβ3 and is internalized in clathrin-coated vesicle.
PLoS ONE Alerts: New Articles Virginie Renaud et al. 2010
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Interestingly, swiggle-mediated inhibition of MT1-MMP clathrin-mediated internalisation was also found to promote MT1-MMP-mediated cell migration.
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Activated MMP-2 containing only 7 disulfide bonds is then internalized in clathrin-coated vesicles and subsequently by an unknown mechanism reachs the cytosol for proteasome degradation.
PLoS ONE Alerts: New Articles Virginie Renaud et al. 2010
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II (COPII) coated vesicles to the Golgi apparatus, and from the Golgi apparatus via adaptor protein (AP) - clathrin-coated vesicles to the plasma membrane.
PLoS ONE Alerts: New Articles Michaela Norum et al. 2010
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