deleterous

"I don't think there's any doubt here that there will be a clear deleterous effect here," said Peter B. Bach, an epidemiologist at Memorial Sloan Kettering Cancer Center in New York who wrote an editorial accompanying the new study.

Study: Hormones up breast cancer deaths Rob Stein 2010

It does have a deleterous effect, and unless quashed trolls tend to be emboldened, mutate, and undermine what confidence people have in the reality of what they're engaging with.

Selectivity 2009

"I 'clar t' goodness-gladness!" exclaimed the colored man, "I am suttinly constrained t 'espress my approbation ob de deleterous manner in which yo' all has come back t 'dis continuous territory."

Lost on the Moon Or, in Quest of the Field of Diamonds Roy Rockwood

People close to the process concede that such a move could have been political dynamite and may have had the deleterous effect of putting shockwaves through the national media and within the province of Quebec.

Stephen Taylor - a blog on Canadian politics 2008

The heart of man is a soil which Nature has made equally suitable to the production of brambles, or of useful grain -- of deleterous poison, or of refreshing fruit, by virtue of the seeds which may he sown in it -- by the cultivation that may be bestowed upon it, In his infancy, those objects are pointed out to him which he is to estimate or to despise, to seek after or to avoid, to love or to hate.

The System of Nature, Volume 1 Paul Henri Thiry Holbach 1756