glargine

Also last year, several epidemiology studies got a lot of attention when they suggested that a synthetic long-acting insulin called glargine seems to increase the risk of cancer.

NPR Topics: News 2010

"Further, inconsistencies in findings within and across individual studies raise concerns as to whether an association between the use of insulin glargine and cancer truly exists," the FDA said, using the scientific name for Lantus.

FDA to Review Safety of Sanofi Drug 2009

Patients treated with BYDUREON experienced significantly greater A1C reduction from baseline, sustained weight loss and a lower risk of hypoglycemia than patients treated with Lantus® insulin glargine after 84 weeks

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The company has decided to focus most of its resources on the ultra-rapid-acting prandial insulin program and to limit funding of its earlier-stage development programs, which include a glucose-sensing basal insulin formulation, a glargine formulation with improved basal characteristics, a stable liquid formulation of glucagon for convenient rescue therapy and pump use, and a sublingual insulin formulation known as VIAtab™.

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LLY and Amylin Pharmaceutical Inc.'s Byetta diabetes drug was approved by the U.S. Food and Drug Administration for a new use -- as an add-on treatment to insulin glargine for some type 2 diabetics.

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Patients were randomized to 52 weeks of treatment with either prandial inhaled insulin plus bedtime insulin glargine or twice daily premixed biaspart insulin (30% short-acting insulin analog, 70% intermediate-acting NPH insulin), both titrated to perceived treatment goals.

MedPageToday.com - medical news plus CME for physicians 2010

Dr. Rodbard was a principal investigator of this study, which was designed to evaluate the safety and efficacy of VIAject® versus regular human insulin when used in combination with insulin glargine.

Latest News from SYS-CON MEDIA 2010

Dr. Rodbard was a principal investigator of this study, which was designed to evaluate the safety and efficacy of VIAject® versus regular human insulin when used in combination with insulin glargine.

RedOrbit News - Technology 2010

"(Blood sugar) reductions were similar across the once-daily and three-times-weekly insulin degludec groups ... and comparable to insulin glargine," Novo said.

FierceBiotech 2010

ORLANDO -- A novel formulation of inhaled insulin (Technosphere), when given at meals with bedtime insulin glargine (Lantus), equals twice-daily premixed biaspart insulin (NovoLog) for glucose control in type 2 diabetes, a randomized trial showed.

MedPageToday.com - medical news plus CME for physicians 2010