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Examples
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HSF1A-dependent activation of Hsp70 and Hsp25 was not detected in hsf1 −/− cells, demonstrating that HSF1A functions in the activation of mammalian protein chaperones through HSF1.
PLoS Biology: New Articles Daniel W. Neef et al. 2010
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Moreover, hsf1 −/− mice inoculated with Rocky Mountain Laboratory prions exhibited a shorter lifespan as compared to wild-type mice
PLoS Biology: New Articles Daniel W. Neef et al. 2010
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(A) HSF1+/+ and hsf1 −/− MEFs were treated with DMSO solvent or increasing concentrations of HSF1A for 15 h or heat shocked for 2 h at 42°C followed by a 15-h recovery.
PLoS Biology: New Articles Daniel W. Neef et al. 2010
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