Definitions
from The Century Dictionary.
- Pertaining to or affected with osteolysis.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of, pertaining to, or causing
osteolysis
Etymologies
Sorry, no etymologies found.
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Examples
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Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases.
unknown title 2011
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DKK1 mutations on bone mass in humans, there is hallmark evidence for an over-production of DKK1 in human cancer cells being responsible for the development of osteolytic lesions associated with metastatic bone disease Albeit Dkk1 can inhibit Wnt signalling through a direct interaction with Lrp5 or Lrp6, its antagonistic function is significantly enhanced by members of the Kremen (Krm) family, which serve as high affinity receptors for Dkk proteins
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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Bu G, Lu W, Liu CC, Selander K, Yoneda T, et al. (2008) Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases.
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases.
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Krm2-deficient mice being older than one year, and it may be worthwhile to analyze the possibility that these mice are protected from tumor-induced osteolytic lesions.
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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(C) Xray analysis (top, scale bars, 1 mm) and µCT scanning (bottom, scale bars, 2 mm) demonstrating the presence of osteolytic lesions in 52 weeks old female
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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These luciferase-expressing osteosarcomas showed conserved osteolytic and osteogenic activities in mice and were detectable by in vivo bioluminescence imaging.
Naturejobs - All Jobs J Rousseau 2010
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Chen Y, Stephens O, Brown N, Chen B, et al. (2008) Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma.
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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A "non-inflammatory" type showing predominantly osteolytic destruction with little disc space narrowing and sclerosis.
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Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, et al. (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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