phospholamban

Used nuclear magnetic resonance imaging to analyze a protein, phospholamban.

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Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, et al. (2006) A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.

PLoS ONE Alerts: New Articles Parveen Sharma et al. 2010

Sugita Y, Kurzydlowski K, De Leon S, Tada M, et al. (2003) Sarcolipin regulates sarco (endo) plasmic reticulum Ca2+-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban.

PLoS ONE Alerts: New Articles Parveen Sharma et al. 2010

Stenoien DL, Knyushko TV, Londono MP, Opresko LK, Mayer MU, et al. (2007) Cellular trafficking of phospholamban and formation of functional sarcoplasmic reticulum during myocyte differentiation.

PLoS ONE Alerts: New Articles Parveen Sharma et al. 2010

Mutagenesis and deletion of cDNA encoding rabbit phospholamban (PLN) containing a deletion of the arginine residue at position 14 has been described in previous publications

PLoS ONE Alerts: New Articles Parveen Sharma et al. 2010

In cardiac muscle, SERCA2a can associate with a 52-amino acid transmembrane phosphoprotein, phospholamban (PLN) [1].

PLoS ONE Alerts: New Articles Parveen Sharma et al. 2010

Western blot analysis detected greatly reduced presence of SR markers (calsequestrin, SERCA2a, and phospholamban) in pRHM, suggesting that the mitochondria-associated particles represented a small subfraction of the SR.

Journal of Biological Chemistry current issue C. Garcia-Perez 2008

Ca2+ sequestration, since the ratio of phosphorylated phospholamban to total phospholamban was sharply reduced in all three mutant hearts.

Journal of Biological Chemistry current issue V. Prasad 2008