Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun   A long-lasting sulfonamide often used to treat or preventmalaria and certaininfections oflivestock .
Etymologies
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Examples
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								The Centers for Disease Control estimates average treatment costs of only 13 cents for chloroquine, 14 cents for sulfadoxine-pyrimethamine, and $2.68 for a seven-day course of quinine. 
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								Prophylaxis in Pregnancy: In endemic areas where prenatal care exists, giving pregnant women sulfadoxine-pyrimethamine (SP) in the latter part of pregnancy can reduce anemia-related deaths and low birthweight. Fighting Malaria - The Time is Now aka TBTAM 2007 
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								High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi. 
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								One set of treatments that was developed to take the place of chloroquine is abbreviated S/P, which stands for two different drugs, sulfadoxine with pyrimethamine. The Edge of Evolution Michael J. Behe 2007 
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								Malawi changed its national policy for malaria treatment in 1993, becoming the first country in Africa to replace chloroquine by sulfadoxine and pyrimethamine combination SP as the first-line drug for uncomplicated malaria. 
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								A total of 52 P. falciparum isolates were also investigated for pyrimethamine and sulfadoxine/pyrimethamine activity against parasite growth according to WHO in vitro standard protocol. 
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								The authors point out that S/P should not be considered a drug combination because the sulfadoxine and pyrimethamine must act synergistically. The Edge of Evolution Michael J. Behe 2007 
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								Similarly, when a mutation in an enzyme abbreviated DHPS changes the alanine normally found at position number 437 to a glycine, sulfadoxine the “S” in the “S/P” fails.1 The Edge of Evolution Michael J. Behe 2007 
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								Nearly all sub-Saharan African countries have switched their national drug policies to phase out old drugs (chloroquine and sulfadoxine-pyrimethamine) that have become useless through resistance and replace them with artemisinin-based combination therapies (ACT), said the report. 
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								A total of 52 P. falciparum isolates were also investigated for pyrimethamine and sulfadoxine/pyrimethamine activity against parasite growth according to WHO in vitro standard protocol. 
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