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Examples
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Burroughs Wellcome has twice reduced the price but still charges $1.20 for every 100-mg capsule -- more than $200 for a month's supply.
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The German drug giant Boehringer Ingelheim reported last November that in a six-month study of more than 1,000 women, a daily 100-mg dose of flibanserin gave premenopausal women 0.8 more
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The German drug giant Boehringer Ingelheim reported last November that in a six-month study of more than 1,000 women, a daily 100-mg dose of flibanserin gave premenopausal women 0.8 more
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In patients with moderate hepatic insufficiency (Child-Pugh score 7 to 9), mean AUC and C max of sitagliptin increased approximately 21% and 13%, respectively, compared to healthy matched controls following administration of a single 100-mg dose of sitagliptin.
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The mean volume of distribution at steady state following a single 100-mg intravenous dose of sitagliptin to healthy subjects is approximately 198 liters.
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This new medication for the relief of moderate to severe acute pain in patients 18 years of age or older is now available by prescription only in 50-mg, 75-mg and 100-mg tablets, announced PriCara, (R)
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As noted, the most common treatment-emergent adverse event was peripheral edema, which was reported in 17\%, 32\%, 36\%, and 29\% of patients in the placebo, darusentan 50-mg, 100-mg, and
theHeart.org 2009
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Co-administration of a single 100-mg oral dose of sitagliptin and a single 600-mg oral dose of cyclosporine increased the AUC and C max of sitagliptin by approximately 29% and 68%, respectively.
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As noted, the most common treatment-emergent adverse event was peripheral edema, which was reported in 17%, 32%, 36%, and 29% of patients in the placebo, darusentan 50-mg, 100-mg, and
theHeart.org 2009
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At the 800-mg dose, peak sitagliptin plasma concentrations were approximately 11 times higher than the peak concentrations following a 100-mg dose.
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