Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A glycoprotein predominantly found on the surface of helper T cells. In humans, it is a receptor for HIV, enabling the virus to gain entry into its host.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • abbreviation immunology A glycoprotein found on the surface of helper T cells; in humans, it enables the HIV virus to enter a cell

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a glycoprotein that is found primarily on the surface of helper T cells

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[c(luster of) d(ifferentiation antigen) 4.]

Support

Help support Wordnik (and make this page ad-free) by adopting the word CD4.

Examples

  • Dot plots - top: gated on CD3+B220 − cells: CD4 versus CD8, middle: gated on SP CD4+ T cells showing the Vβ8. 2+ tumor cell population and an irrelevant Vβ-chain (Vβ6); bottom: gated on DP CD4/Vβ8. 2 as shown in histogram all other Vβ-families were negative.

    PLoS ONE Alerts: New Articles Silke H. Raffegerst et al. 2009

  • An international team has developed the prototype CD4 rapid test, similar in design to a home pregnancy test, which works with a finger-prick blood sample to measure the numbers of CD4+ T-cells in a person's blood.

    Bloggers.Pakistan 2009

  • (B-D) Foxp3 expression in splenic CD4+ T cells 8 (B) or 14 (C) d after infection, and in sub-mandibular lymph node CD4

    PLoS Biology: New Articles 2009

  • More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.

    EurekAlert! - Breaking News 2009

  • More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.

    unknown title 2009

  • In order to define the target antigens and the relative immunodominance of the overall HIV-1-specific CD4 T cell response in clade C virus infection, we used an IFN-γ Elispot assay to screen for HIV-1-specific CD4+ responses using an overlapping peptide set spanning the entire HIV-1 clade C proteome in 32 randomly selected subjects.

    PLoS ONE Alerts: New Articles 2009

  • An international team has developed the prototype CD4 rapid test, similar in design to a home pregnancy test, which works with a finger-prick blood sample to measure the numbers of CD4+ T-cells in a person's blood.

    rediff.com 2009

  • More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.

    EurekAlert! - Breaking News 2009

  • +CD8 − lymphocytes, which are further referred to as CD4

    PLoS ONE Alerts: New Articles Joost Smolders et al. 2009

  • HIV infects immune cells called CD4 T-cells (also called helper T cells) and slowly begins to decrease their numbers.

    Dr. Andrew Lange: How to Get a Sexually Transmitted Disease Without Having Sex 2010

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.