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Examples
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Image J software analysis confirmed that M-CSF enhanced Sp1 nuclear localization compared to untreated monocytes (p M-CSF up-regulates VEGF mRNA transcription in an ERK - and Sp1-dependent manner Next, we examined the role of Erk and Sp1 in the transcriptional regulation of VEGF mRNA.
PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008
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In cancer cells, activated “Ras” chronically and permanently activates Mek, which permanently activates Erk, resulting in uncontrolled cell division—pathological mitosis.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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In cancer cells, activated “Ras” chronically and permanently activates Mek, which permanently activates Erk, resulting in uncontrolled cell division—pathological mitosis.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Ras may be activated in one sample of bladder cancer; Mek in another; Erk in the third—but in each case, some vital piece of the Ras-Mek-Erk cascade was dysregulated.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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But the activated ras pathway Ras→ Mek → Erk does not merely cause accelerated cell division; the pathway also intersects with other pathways to enable several other “behaviors” of cancer cells.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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But the activated ras pathway Ras→ Mek → Erk does not merely cause accelerated cell division; the pathway also intersects with other pathways to enable several other “behaviors” of cancer cells.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Show Notes « Erk Pod - “All Erk, all the time … .. and then some!”
TeeMorris.com » Blog Archive » A High Tech Voting Experience 2008
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Ras may be activated in one sample of bladder cancer; Mek in another; Erk in the third—but in each case, some vital piece of the Ras-Mek-Erk cascade was dysregulated.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Mek in turn activates Erk, which, through several intermediary steps, ultimately accelerates cell division.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Mek in turn activates Erk, which, through several intermediary steps, ultimately accelerates cell division.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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