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Examples
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They believe that drugs that target the enzyme called GSK3 could help to slow memory loss and calm the symptoms of epileptic seizures.
Telegraph.co.uk: news, business, sport, the Daily Telegraph newspaper, Sunday Telegraph 2010
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The researchers found that the chemicals worked by blocking an enzyme, called GSK3, that can control when the stem cell switches to a more specialised cell type.
PhysOrg.com - latest science and technology news stories 2009
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Although LeTx influences macrophage physiology and causes defects of some key signaling pathways such as GSK3β which contributes to cytotoxicity, these results indicate that modulation of NF-κB by p50, p100 and Jmjd3 could be vital for the recovery of murine macrophages from exposure to the anthrax lethal toxin.
Elites TV PLoS ONE 2010
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Although LeTx influences macrophage physiology and causes defects of some key signaling pathways such as GSK3β which contributes to cytotoxicity, these results indicate that modulation of NF-κB by p50, p100 and Jmjd3 could be vital for the recovery of murine macrophages from exposure to the anthrax lethal toxin.
Elites TV PLoS ONE 2010
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Meanwhile, the transcriptional and expressive levels of GSK3 beta and CDK5 in the brains were tested.
BioMed Central - Latest articles Rong Wang 2010
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"Our recent finding was particularly interesting because one of the actions of lithium, the most common mood disorder drug, is to inhibit GSK3?." explains Dr. Tsai.
PhysOrg.com - latest science and technology news stories 2010
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They found that the GSK3 enzyme helps to suppress brain activity by reducing the flow of chemical messages sent between brain cells.
Telegraph.co.uk: news, business, sport, the Daily Telegraph newspaper, Sunday Telegraph 2010
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Dixdc1 and DISC1 interacted to regulate neural progenitor proliferation via modulation of Wnt/GSK3? signaling.
PhysOrg.com - latest science and technology news stories 2010
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The team warns, however, that because GSK3 is associated with a range of body and brain functions, more research is needed to establish what the effects of manipulating this enzyme might be.
Telegraph.co.uk: news, business, sport, the Daily Telegraph newspaper, Sunday Telegraph 2010
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Additionally, it showed higher CDK5, but lower GSK3 beta transcriptional and expressive levels in the brains of scrapie-infected animals.
BioMed Central - Latest articles Rong Wang 2010
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