Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • French noble family including Francis of Lorraine, Second Duke of Guise (1519–1563), a military leader who defeated Holy Roman Emperor Charles V and battled the Huguenots. His son Henry of Lorraine, Third Duke of Guise (1550–1588), helped plan the St. Bartholomews' Day massacre of Huguenots in 1572 and was later assassinated by order of Henry III.

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