from The American Heritage® Dictionary of the English Language, 5th Edition.
- transitive verb To transform the appearance and character of (a city) by constructing tall and densely situated buildings.
Sorry, no etymologies found.
When I asked Martha why Berkeley needs more "open government," her reply was "so we can stop the City Council from making deals to Manhattanize Berkeley with 22-story towers that will just fall down in an earthquake."
I suspect as the rail connections thicken into downtown LA, the more that area will Manhattanize.