Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun An experimental acetylcholinesterase inhibitor under investigation for the treatment of functional dyspepsia.

Etymologies

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Examples

  • Zeria Pharmaceutical (TOKYO: 4559) (ISIN: JP3428850006) announced today positive results of their Japanese Phase III study of Z-338 (acotiamide hydrochloride hydrate; "acotiamide") for the treatment of functional dyspepsia (FD).

    The Earth Times Online Newspaper 2010

  • The clinical trial was a multicenter, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of acotiamide 100 mg three times a day for 4 weeks in patients with FD.

    The Earth Times Online Newspaper 2010

  • Zeria will obtain marketing authorization and manufacture acotiamide, and thereafter both companies will co-market acotiamide in Japan with a single brand name.

    The Earth Times Online Newspaper 2010

  • The findings definitively demonstrated that acotiamide alleviated the symptoms of FD patients.

    The Earth Times Online Newspaper 2010

  • Acetylcholine is an important neurotransmitter for gastrointestinal motility, and acotiamide inhibits peripheral acetylcholinesterase activities resulting in the improvement of delayed gastric emptying, and consequently the symptoms of FD.

    The Earth Times Online Newspaper 2010

  • In both of two primary endpoints employed in the present study, acotiamide was statistically significantly effective when compared to placebo.

    The Earth Times Online Newspaper 2010

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