from The American Heritage® Dictionary of the English Language, 4th Edition
- n. See alcoholism.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. excessive use of alcohol and alcoholic drinks
Sorry, no etymologies found.
H. H. Leenen, R. B. Stewart, and L. A. Grupp, Angiotensin converting enzyme inhibitors: animal experiments suggest a new pharmacological treatment for alcohol abuse in humans, Alcoholism: Clinical and Experimental Research, 12 1988: 65-70.
They concluded that certain types of alcohol abuse may be biochemically similar to the eating disorder known as Bulimia or “binge eating” which, in turn, may be linked to increased opioid activity.
Although he was unable to find salsolinol without this chemical manipulation, Collins felt that it was probable that long-term alcohol abuse would lead to vitamin deficiencies and liver damage, and that these deficiencies, in turn, would increase acetaldehyde levels—leading to the formation of TIQs.
In families with male-limited susceptibility, alcohol abuse is found to be nine times greater in the adopted sons, regardless of the environment after their adoption.8
Additional confirmation came in 1978 when Michael Bohman at Umea University in Sweden compared rates of alcohol abuse in 2,324 adoptees and their biological parents.
Milieu-limited alcohol abuse tends to have its onset after 25 years of age.
The significance of these findings is that long-term alcohol abuse reduces the formation and activity of this protein, causing a reduction of activity in the cyclic AMP second-messenger system, resulting in reduced neural firing.