Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A steroid hormone secreted by the adrenal cortex that regulates the salt and water balance in the body.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A mineralocorticoid hormone, secreted by the adrenal cortex, that regulates the balance of sodium and potassium in the body.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a corticosteroid hormone that is secreted by the cortex of the adrenal gland; regulates salt (sodium and potassium) and water balance

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[ald(ehyde) + ster(ol) + –one.]

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Examples

  • Pfizer's pill failed because it unexpectedly increased levels of a hormone called aldosterone, linked to fatty plaque buildup and high blood pressure.

    BusinessWeek.com -- Top News 2010

  • Pfizer's pill failed because it unexpectedly increased levels of a hormone called aldosterone, linked to fatty plaque buildup and high blood pressure.

    Merck Restarts Cholesterol Race Four Years After Pfizer Failure - Bloomberg 2010

  • Dr. Michael Alderman, a blood pressure researcher at Albert Einstein College of Medicine and editor of the American Journal of Hypertension, said in an email, The problem with reducing sodium enough to change blood pressure is that it has other effects -- including increasing insulin resistance, increasing sympathetic nerve activity, and activating the renin-angiotensin system and increasing aldosterone secretion.

    Kristin Wartman: Change in Season: Why Salt Doesn't Deserve Its Bad Rap Kristin Wartman 2011

  • If one lowers sodium intake to lower blood pressure, this change in sodium activates several systems including the renin-angiotensin aldosterone system that conserve sodium, and those systems are implicated in disease processes such as damaging the arterial wall and kidneys, Staessen says,This study may apply to Americans of white European descent, but it might less applicable to blacks because they are believed to be more salt sensitive, he says.

    Study: Lower salt intake could be riskier than thought 2011

  • If one lowers sodium intake to lower blood pressure, this change in sodium activates several systems including the renin-angiotensin aldosterone system that conserve sodium, and those systems are implicated in disease processes such as damaging the arterial wall and kidneys, Staessen says,This study may apply to Americans of white European descent, but it might less applicable to blacks because they are believed to be more salt sensitive, he says.

    Study: Lower salt intake could be riskier than thought 2011

  • Dr. Michael Alderman, a blood pressure researcher at Albert Einstein College of Medicine and editor of the American Journal of Hypertension, said in an email, The problem with reducing sodium enough to change blood pressure is that it has other effects -- including increasing insulin resistance, increasing sympathetic nerve activity, and activating the renin-angiotensin system and increasing aldosterone secretion.

    Kristin Wartman: Change in Season: Why Salt Doesn't Deserve Its Bad Rap Kristin Wartman 2011

  • There was no increase in blood pressure and no increase in levels of aldosterone or cortisol, two hormones that were elevated in the earlier Pfizer torcetrapib trial.

    UPDATE: Lilly Study Shows Experimental Drug Boosts Good Cholesterol Jennifer Corbett Dooren 2011

  • The Big C Gets Its Own Biography Brain Scan Reveals Source of Anxiety Triathlons Keep 70-Year-Old Neurosurgeon Young Scientists now believe that torceptrapib had deleterious effects on the heart because it raised blood pressure and increased levels of substances called electrolytes and a hormone called aldosterone.

    Cholesterol Drug Advances Ron Winslow 2010

  • Bile contains bile salts, which emulsify (break down) fats in the digestive tract and aid in the absorption of fat molecules as well as the fat soluble vitamins, Vitamin A, Vitamin D, Vitamin E and Vitamin K. Cholesterol is an important molecule for the synthesis of Vitamin D and the steroid hormones, including the adrenal gland hormones; cortisol and aldosterone as well as the sex hormones progesterone, estrogen, and testosterone.

    Dr. M.J. Wegmann: Top 10 Foods to Lower Your Cholesterol 2009

  • The study also found that lead exposure was associated with a decrease in circulating aldosterone levels.

    Even Low Levels of Lead Dangerous for Children GreenFertility 2009

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