Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective medicine Acting to inhibit or reduce
fibrosis - noun A drug that inhibits or reduces
fibrosis
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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FXR is also expressed in the intestine and kidney and INT-747 exhibits similar protective antifibrotic effects in animal models of inflammatory bowel disease and diabetic nephropathy.
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FXR is also expressed in the intestine and kidney and INT-747 exhibits similar protective antifibrotic effects in animal models of inflammatory bowel disease and diabetic nephropathy.
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Most of the current pharmacological treatments for PD are not based on antifibrotic approaches that have shown promising results in animal models and clinical efficacy in other fibrotic conditions, which may explain why they are generally unsuccessful.
Naturejobs - All Jobs Nestor F. Gonzalez-Cadavid 2010
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At the same time, a steady overexpression of inducible nitric oxide synthase, leading to increased nitric oxide and cGMP levels, seems to act as an endogenous antifibrotic mechanism.
Naturejobs - All Jobs Nestor F. Gonzalez-Cadavid 2010
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FXR is also expressed in the intestine and kidney and INT-747 exhibits similar protective antifibrotic effects in animal models of inflammatory bowel disease and diabetic nephropathy.
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Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategy
Naturejobs - All Jobs Nestor F. Gonzalez-Cadavid 2010
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Complex interaction of TGF-beta1 with profibrotic function and TGF-beta3 with antifibrotic function may increase synthesis of collagens and thereby significantly contribute to the process of gluteal muscle scarring in patients with GMC.
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To date, as equally cheap, effective and well-supported antifibrotic therapies are hard to be found, the authors predict that this property will put ARBs in the pole position for treating at least the liver fibrosis.
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To date, as equally cheap, effective and well-supported antifibrotic therapies are hard to be found, the authors predict that this property will put ARBs in the pole position for treating at least the liver fibrosis.
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Dutreil M, Fattman C, Pandey AC, Torres G, et al. (2007) Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury.
PLoS ONE Alerts: New Articles Susana Aguilar et al. 2009
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