Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry, genetics any
subsequence ofnucleic acid orprotein , selected from a largerandom sequence -pool , used tobind to aspecific target molecule
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The term aptamer means something like "fitting pieces" (from the Latin word aptus, meaning to fit, and the Greek word meros, meaning piece).
Nano Tech Wire 2009
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This particular type of aptamer, which is synthetic, is usually floppy.
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SELEX (systematic evolution of ligands by exponential enrichment) is a method to generate DNA … which are then eluted from the target molecule and amplified by PCR. … (both of which are used in Macugen, an FDA-approved aptamer), … The development of aptamer probes for molecular signatures on the cancer cell …
"War of the Weasels" article in new Skeptical Inquirer - The Panda's Thumb 2010
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Selection of a DNA aptamer for homocysteine using SELEX from Maureen McKeague on Vimeo.
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Today, we're going to learn about the "Selection of a DNA aptamer for homocysteine using Systematic Evolution of Ligands by Exponential Enrichment."
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Click to see a dance routine to “Selection of a DNA aptamer for homocysteine using systematic evolution of ligands by exponential enrichment.”
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In a stylish routine fueled by Queen, the Supremes and Lady Gaga, the members of the DeRosa Lab at Carleton University shimmy and shake their way through the the scientific process of finding a DNA aptamer to attach to the molecule homocysteine.
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Publisher: Information Gatekeepers, Inc. Archemix announces aptamer-based therapeutics agreement with Johnson
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Archemix announces aptamer-based therapeutics agreement with Johnson
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The detector works by passing an electronic signal through a type of DNA molecule, called an aptamer, that binds with other specific molecules, in this case cocaine.
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Whereas most biosensors use antibodies or enzymes to target proteins, Gao’s relies on aptamers — short bits of single-stranded DNA or RNA that are designed to fold such that they bind to targets ranging from small molecules to toxins.
Wearable biosensor measures fertility hormones in sweat Amanda Heidt 2023
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