Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
arrestin .
Etymologies
Sorry, no etymologies found.
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Examples
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Ghrelin induces a first "wave" of c-Src activation via G protein-dependent signaling that it is followed by a second wave of c-Src activation via β-arrestins-mediated signaling
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Ahn S, Lefkowitz RJ, Shenoy SK (2007) Beta-arrestins and cell signaling.
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Luttrell LM, Lefkowitz RJ (2002) The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals.
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Lefkowitz says the discovery opens the door to the possibility of developing a "biased ligand," a drug that would trigger GP109A, but not the beta-arrestins.
PhysOrg.com - latest science and technology news stories 2009
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This receptor, in turn, alerts other sets of proteins, including G proteins and a group referred to as beta-arrestins.
PhysOrg.com - latest science and technology news stories 2009
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The finding reinforces some of Lefkowitz's recent research that demonstrated that beta-arrestins, which often work in tandem with G proteins, can sometimes work independently of them, initiating their own signals.
PhysOrg.com - latest science and technology news stories 2009
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We assayed flies carrying an extra genomic copy of arrestin2 or arr2 (p [w+; arr2]; gift of L. Zweibel), one of the fly "sensory" arrestins.
PLoS ONE Alerts: New Articles Valerie L. Kilman et al. 2009
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Milano SK, Benovic JL (2007) Regulation of receptor trafficking by GRKs and arrestins.
PLoS ONE Alerts: New Articles Anahi Molla-Herman et al. 2008
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