Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of several
intramolecular interactions thatregulate protein function
Etymologies
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Examples
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Vardar-Ulu D, Histen G, Sanchez-Irizarry C, Aster JC, et al. (2007) Structural basis for autoinhibition of Notch.
PLoS ONE Alerts: New Articles Miguel Aste-Amézaga et al. 2010
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The two-stage activation pathway and the autoinhibition mechanism, which are probably shared by other members of the
Journal of Biological Chemistry current issue Y.-j. Xu 2009
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Graves BJ (2000) Phosphorylation represses ETS-1 DNA by reinforcing autoinhibition.
PLoS ONE Alerts: New Articles He-Ge Chen et al. 2009
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ABL family tyrosine kinases are tightly regulated by autoinhibition and phosphorylation mechanisms.
Journal of Biological Chemistry current issue X. Cao 2008
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These findings are consistent with an allosteric kinase activation mechanism by which RIN1 binding promotes a more accessible ABL catalytic site through relief of autoinhibition.
Journal of Biological Chemistry current issue X. Cao 2008
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