bisphosphonate love

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of a class of drugs that decrease bone resorption by inhibiting osteoclasts, used in the treatment of osteoporosis, Paget's disease, bone metastases, and other conditions.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun chemistry Any of a class of organic compounds having two phosphate groups attached to a single carbon atom
  • noun medicine Several pharmaceuticals, having this structure, that are used to treat Paget's disease by restricting bone loss

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[bis– + phosphon(ic acid), phosphorous acid (from phosphonium) + –ate.]

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Examples

  • However, as these new studies point out, more research is needed to clarify the effects of long-term bisphosphonate use on bone quality.

    Boning up on the link between Fosamax and atypical fractures 2010

  • However, as these new studies point out, more research is needed to clarify the effects of long-term bisphosphonate use on bone quality.

    Boning up on the link between Fosamax and atypical fractures 2010

  • In conducting a review of the patients 'charts, the doctors found that the 63 patients, diagnosed with ONJ over a 3-year period, shared one commonality, they all had received long-term bisphosphonate therapy.

    Fosamax Does More Harm Than Good 2006

  • Of most concern, however, is that long-term bisphosphonate users can develop rare and unusual fractures in the thigh bone, or femur.

    latimes.com - News 2010

  • "Recent research suggests that suppressed bone remodeling from long-term bisphosphonate use might result in brittle bone that is prone to atypical fractures," said Gladnick.

    PhysOrg.com - latest science and technology news stories PhysOrg Team 2010

  • Of most concern, however, is that long-term bisphosphonate users can develop rare and unusual fractures in the thigh bone, or femur.

    latimes.com - News 2010

  • "Recent research suggests that suppressed bone remodeling from long-term bisphosphonate use might result in brittle bone that is prone to atypical fractures," said Gladnick.

    Science Blog BJS 2010

  • "This tells us that there may be some measurable differences in bone quality parameters in patients on long-term bisphosphonate therapy, which might contribute to the development of atypical fractures."

    Science Blog BJS 2010

  • "This tells us that there may be some measurable differences in bone quality parameters in patients on long-term bisphosphonate therapy, which might contribute to the development of atypical fractures."

    PhysOrg.com - latest science and technology news stories PhysOrg Team 2010

  • What's your risk of an adverse effect of long-term bisphosphonate therapy?

    All MayoClinic.com Topics 2008

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