from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine
treatmentof a tumourwith a medicationin order to make it more susceptibleto radiationtreatment
from Wiktionary, Creative Commons Attribution/Share-Alike License
The sensitization effect of certain substances with regard to other chemicals - referred to as the chemosensitization effect by scientists - does not play a role in the current legislation.
The CK2 protein expression levels were determined and the effect of its down-regulation on chemosensitization of pancreatic cancer cells was investigated.
BioMed Central - Latest articles Jan Kreutzer 2010
Our results demonstrate that in p53-deficient human gastric cancer cells, restoration of functional miR-34 inhibits cell growth and induces chemosensitization and apoptosis, indicating that miR-34 may restore p53 function.
Finally, our studies suggest a molecular link between the inhibition of GRP78 / BIP and E2F1-mediated chemosensitization of tumor cells, underscoring its relevance for cancer treatment.
Journal of Biological Chemistry current issue T. Racek 2008
Interestingly, AGS KD cells transfected with si p53 were significantly less susceptible to growth inhibition by 5-FU than AGS KD cells transfected with control siRNA (siRNA silencing of p53 reverses the chemosensitization of AGS KD cells.
PLoS ONE Alerts: New Articles Nadine Rohwer et al. 2010