Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Having the ability to form
clones
Etymologies
Sorry, no etymologies found.
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Examples
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The adult heart contains cardiac stem cells (CSCs) that are self-renewing, clonogenic (able to produce identical daughter cells), and multipotent-ie, they differentiate into all three major cardiac lineages (myocytes, vascular smooth muscle cells, and endothelial cells).
Forbes.com: News Larry Husten 2011
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So, unless the test is able to discriminate, in the cancer cells present in the blood at any given stage of a patient's disease, those cells that will "home", are "clonogenic", etc., it does really not shed much light into prognostication on a patient's urvival, necessity of changing therapeutic plans, etc...
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The adult heart contains cardiac stem cells (CSCs) that are self-renewing, clonogenic (able to produce identical daughter cells), and multipotent-ie, they differentiate into all three major cardiac lineages (myocytes, vascular smooth muscle cells, and endothelial cells).
unknown title 2011
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The fact that a cancer cell is found in the blood does in no way mean that it will home in a particular tissue/site and start growing a give rise to a "metastasis"... that cancer cell in the blood should also prove to be "clonogenic", i.e., be capable of replication, survival skills such as angiogenetic mechanisms i.e., provide itself with enough blood supply to grow when it has passed the 1 mm size mark.
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ErPC3 was cytotoxic to AML primary cells and reduced the clonogenic activity of CD34
Naturejobs - All Jobs A M Martelli 2010
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Interestingly, when cultured in foetal calf serum (FBS) or human cord blood serum, MPCs were able to differentiate into highly proliferative and clonogenic MSCs.
PLoS ONE Alerts: New Articles Simone Pacini et al. 2010
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(E) The clonogenic potential of the test expanded cells showed a significant increase in the differential colony formation.
PLoS ONE Alerts: New Articles Sangeetha V. M et al. 2010
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Results showed that C4-2 cells were more likely to survive from irradiation and appeared more aggressive in their resistance to radiation treatment compared with LNCaP, as measured by clonogenic assays and cell viability and cell cycle analyses.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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We found that overexpression or inhibition of let-7g, miR-189, and miR-20a markedly influenced clonogenic survival and cell proliferation per se.
BioMed Central - Latest articles Mechthild Wagner-Ecker 2010
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ErPC3 was cytotoxic to AML primary cells and reduced the clonogenic activity of CD34
Naturejobs - All Jobs A M Martelli 2010
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