Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Plural form of coactivator.

Etymologies

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Examples

  • Kobayashi K, Gao P, Griffin JD (2002) Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

    PLoS ONE Alerts: New Articles Miguel Aste-Amézaga et al. 2010

  • V, Kemler R (2000) The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates.

    PLoS Biology: New Articles Dimple Notani et al. 2010

  • The C-terminus of β-catenin is indispensable for the transactivation function, presumably since it harbours binding sites for transcriptional coactivators such as p300/CBP and TBP

    PLoS Biology: New Articles Dimple Notani et al. 2010

  • Pugh BF, Tjian R (1990) Mechanism of transcriptional activation by Sp1: evidence for coactivators.

    PLoS ONE Alerts: New Articles Anil K. Singh et al. 2010

  • Sik1 is known to regulate transcription through inhibitory phosphorylation of a family of CREB coactivators, called TORCs/CRTCs, and that down-regulation of sik1 would be expected to increase the expression of CREB target genes

    PLoS ONE Alerts: New Articles Antonio Romito et al. 2010

  • Song L, Aster JC, Blacklow SC (2006) Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.

    PLoS ONE Alerts: New Articles Miguel Aste-Amézaga et al. 2010

  • "Biological control through regulated transcriptional coactivators".

    Citizendium, the Citizens' Compendium - Recent changes [en] 2009

  • Importantly, inhibition of RNF6 or interference with ubiquitination of AR altered expression of a specific group of AR target genes and abrogated recruitment of AR and its required coactivators to androgen-responsive regulatory regions in these genes.

    PhysOrg.com - latest science and technology news stories 2009

  • NICD then translocates to the nucleus and collaborate with DNA binding protein CSL / RBP-Jk along with coactivators leading to the transcription of its target genes

    PLoS ONE Alerts: New Articles Kushagra Bansal et al. 2009

  • "Biological control through regulated transcriptional coactivators".

    Citizendium, the Citizens' Compendium - Recent changes [en] 2009

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