Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An anomaly of the eye, usually a developmental defect, that often results in some loss of vision.

from The Century Dictionary.

  • noun In medicine: The part taken away in mutilation; a mutilation; a defect.
  • noun A defect in the iris, choroid, retina, optic nerve, or lens, due to incomplete or perverted closing of the choroidal fissure: also used for other fissures in the eye or its lids.

from the GNU version of the Collaborative International Dictionary of English.

  • noun (Anat. & Med.) A defect or malformation; esp., a fissure of the iris supposed to be a persistent embryonic cleft.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun An abnormal hole present from birth in one of the structures of the eye, such as the lens, eyelid, or retina.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[New Latin colobōma, from Greek kolobōma, part removed in mutilation, from koloboun, to mutilate, from kolobos, maimed.]

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