Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of a class of
transmembrane proteins that form assembled structures invertebrates
Etymologies
Sorry, no etymologies found.
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Examples
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Experiments showed that the process relied on the presence of a protein channel called connexin 43 on the surface of melanoma cells ..
Latest Science News Features, Blog Entries, Column Entries, Issues, Articles and Book Reviews 2010
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Experiments showed that the process relied on the presence of a protein channel called connexin 43 on the surface of melanoma cells ..
Latest Science News Features, Blog Entries, Column Entries, Issues, Articles and Book Reviews 2010
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For instance, targeting of genes encoding components of the contractile apparatus in cardiomyocytes leads to cardiomyopathy; targeted mutations in connexin proteins of gap junctions cause conduction defects; disrupted genes for transcription factors involved in heart development lead to congenital heart malformations; and targeting of genes controlling energy metabolism causes cardiomyopathy.
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information 2007
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This process relies on connexin 43, a protein that forms tiny communication channels between different types of cells.
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Rescigno and colleagues found that injecting salmonella into cancerous mice and melanoma cells from humans increased the amount of connexin 43 in the tumor cells.
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But as cancer cells grow and proliferate, they can become invisible to immune cells because not enough connexin 43 is made to keep the "red flag" process going.
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This process relies on connexin 43, a protein that forms tiny communication channels between different types of cells.
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The project will focus on the development of new models of connexin and pannexin inactivation in mature astrocytes, to study the functions of these molecules in neuroglial and gliovascular interactions in the mouse brain.
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Rescigno and colleagues found that injecting salmonella into cancerous mice and melanoma cells from humans increased the amount of connexin 43 in the tumour cells.
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But as cancer cells grow and proliferate, they can become invisible to immune cells because not enough connexin 43 is made to keep the "red flag" process going.
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