Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
coregulator .
Etymologies
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Examples
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This review provides a brief synopsis of the AR structure, AR coregulators, posttranslational modifications of AR, duality of AR function in prostate epithelial and stromal cells, AR-dependent signaling, genetic changes in the form of somatic and germline mutations and their known functional significance in PCa cells and tissues.
Naturejobs - All Jobs Shahriar Koochekpour 2010
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Auboeuf D, Honig A, Berget SM, O'Malley BW (2002) Coordinate regulation of transcription and splicing by steroid receptor coregulators.
PLoS ONE Alerts: New Articles Andrea Vambutas et al. 2009
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Auboeuf D, Honig A, Berget SM, O'Malley BW (2002) Coordinate regulation of transcription and splicing by steroid receptor coregulators.
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Occupancy of AR and coregulators at PSA and TGM loci.
PLoS ONE Alerts: New Articles Li Jia et al. 2008
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Analysis of the AROR sequences, followed by site-directed ChIP, identified binding sites for AR transcriptional coregulators FoxA1, CEBPβ, NFI and GATA2, which had diverse effects on endogenous AR target gene expression levels in siRNA knockout experiments.
PLoS ONE Alerts: New Articles Li Jia et al. 2008
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Upon entering the nucleus, AR then organizes into thousands of discrete but unstable foci (referred to as the hyperspeckled pattern), interacts with coregulators and members of the general transcriptional apparatus, and regulates gene expression by interacting with androgen response elements associated with androgen-regulated genes.
PLoS ONE Alerts: New Articles Adam T. Szafran et al. 2008
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The differences in the amount of speckling observed following exposure to the various compounds used could reflect differences in the identity of the recruited coregulators and / or the strength of AR-CoR binding
PLoS ONE Alerts: New Articles Adam T. Szafran et al. 2008
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Only a small number of ARORs is actually engaged in transcriptional regulation possibly again due to the presence of another set of coregulators (Y & Z) that may convert poised ARORs to engaged ones.
PLoS ONE Alerts: New Articles Li Jia et al. 2008
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Occupancy of AR and coregulators in LNCaP and C4-2B cells.
PLoS ONE Alerts: New Articles Li Jia et al. 2008
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As a matter of fact, there are likely dozens more coregulators that determine AR activity across all ARORs and cell types.
PLoS ONE Alerts: New Articles Li Jia et al. 2008
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