Definitions

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  • noun Plural form of corepressor.

Etymologies

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Examples

  • Two major corepressors, SMRT (silencing mediator for retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor), have been shown to mediate repression associated with nuclear receptors and a myriad of other transcription factors.

    BioMed Central - Latest articles Kristopher J Stanya and Hung-Ying Kao 2009

  • Like most other nuclear receptors that form heterodimers with RXRs, LXRs reside within the nucleus, bound to LXR response elements (LXREs) and complexed with corepressors.

    PLoS ONE Alerts: New Articles Li Zhou et al. 2009

  • Recent studies have shown that FOXP3 is an acetylated protein in a large nuclear complex and FOXP3 actively represses transcription by recruiting enzymatic corepressors, including histone modification enzymes.

    Proceedings of the National Academy of Sciences current issue 2008

  • These findings demonstrate an important role for corepressors SMRT and NCoR in the regulation of β-catenin-TCF4-mediated

    Journal of Biological Chemistry current issue 2008

  • Grunseich C, Lu DD, Speh JC, Mandel G (2005) REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

    PLoS ONE Alerts: New Articles Yuh-Man Sun et al. 2008

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