corrin

The interatomic distances in the inner ring of factor VIa, which has been called the corrin ring, conform very closely with the distances proposed 12 for a structure containing six resonating double bonds, so closely as to leave almost no doubt of the correct formulation of its chemical structure (cf.Fig. 9).

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

[ORIGINAL MARGINAL NOTE IN MANUSCRIPT:] corrin: 15: 42

My Name Was Martha: A Renaissance Woman's Autobiographical Poem 1993

In nickel corrin, the distortion is small but very regular and tetrahedral in character in relation to the nickel atom; alternate nitrogen atoms, bonded to it, lie above and below the least squares plane passing through the nickel and four nitrogen atoms.

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

Again an important part in the analysis was played by our having a view of the corrin nucleus surrounding the cobalt atom in quite different crystals, the cyanocobalamin crystals and also some, or perhaps

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

It was all the same, quite a moment in my life when J.D. Dunitz showed last summer at the Royal Society very closely similar figures derived by the X-ray analysis of the nickel corrin derivative synthesized early this year by Eschenmoser and his coworkers 18.

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

In the unsubstituted compounds, and particularly in cobyric acid, the deviations are in the same sense as in the nickel corrin derivative and as in this molecule, C-5 and C-15, which carry C-35 and

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

One can see features of the system that might be important, the variable valency of cobalt and the possibility of changes within the corrin nucleus, the fact that the cobalt to carbon bond readily breaks to give rise to free radicals 21.

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

One of the features of the corrin nucleus in the natural compounds is that even the inner ring is not quite planar.

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

Very recently, Dunitz and Meyer have refined the nickel corrin structure through several more stages; their latest interatomic distances shown in Fig. 11 are now so close to the earlier proposed theoretical figures that one begins to feel that the small remaining deviations are likely to be real, e.g. in C-N

Nobel Lecture The X-Ray Analysis Of Complicated Molecules 1964

It can also link to a cyanide group as in Vitamin B12. molecule consists of a corrin ring, that has several fused sidegroups.

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