cortin

By that time biochemists had sufficient experience with hormones to be quite certain that the OUR ADRENAL CORTEX -7 extract, called cortin, had to contain at least one hormone.

The Human Brain Asimov, Isaac 1963

Huius per tria latera dependent retia seu cortin� de cordulis sericis, in quibus ad singulos nodos, grossa margarita habetur innexa, quibus cortinis tegitur officina: in eius concauitate tenetur tumba quadrata, in qua conueniunt conductus omnium potuum, qui bibuntur in Curia, et innumera vasorum genera, quibus potus omnibus ministratur.

The Principal Navigations, Voyages, Traffiques and Discoveries of the English Nation 2003

As all the cortin substances are closely related to one another, Reichstein's finding implies that, like the sex hormones, they belong to the large and important group of steroids.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

Side by side with the production in pure form of the cortin substances, their chemical structures were elucidated.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

The isolation of the cortin proved to be a difficult task, calling for the combined efforts of a number of research workers.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

As long as efforts were confined chiefly to soaking out the active factor, or the cortin as it was called, with water, the results obtained were uneven and none too convincing.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

As early as in 1934, Kendall and his group succeeded in preparing from cortex extract what was at first assumed to be pure cortin in crystalline form.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

With that the foundation was laid for further research, and it now seemed possible to produce the cortin in pure form and establish its nature.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

In conjunction with Kendall, Hench began to treat cases of chronic rheumatoid arthritis with cortin, but without success.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964

The demonstration of the fact that the active principle also passes into many organic solvents, such as alcohol, ether, benzene, etc., guided Swingle and Pfiffner to a method for producing the cortin, which yielded a product by means of which the experimental animals could easily be kept alive for months.

Nobel Prize in Physiology or Medicine 1950 - Presentation Speech 1964