Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
costimulator .
Etymologies
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Examples
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If the antigen does, indeed, represent a threat, the APC should express molecules called costimulators, which provide the second signal-the alarm that tells the T cell to proliferate and respond.
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Wolf SF, Unanue ER (1993) Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.
PLoS ONE Alerts: New Articles Diederik van de Wetering et al. 2009
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If costimulators are not present, the T cell should either die or become ineffective.
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