Definitions
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys
Etymologies
Sorry, no etymologies found.
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Examples
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But the risk was increased by 18 percent by NSAIDS that acted against cox-1, compared to a 60 percent increase for those with the greatest cox-2 activity.
NewsInferno 2009
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A newer generation of NSAIDs that act against cox-2 reduce the gastrointestinal bleeding, pain and inflammation that are major side effects of the cox-1 drugs, but they have been found to increase the risk of heart attack and stroke.
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"We found a significant correlation between the degree of inhibition in vitro [in the laboratory] of whole blood cox-2, but not whole blood cox-1," said the report by researchers in Spain and Italy.
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A newer generation of NSAIDs that act against cox-2 reduce the gastrointestinal bleeding, pain and inflammation that are major side effects of the cox-1 drugs, but they have been found to increase the risk of heart attack and stroke.
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But the risk was increased by 18\% by drugs acting primarily against cox-1, compared to a 60\% increase for those with the greatest cox-2 activity.
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A newer generation of NSAIDs that act against cox-2 reduce the gastrointestinal bleeding, pain and inflammation that are major side effects of the cox-1 drugs, but they have been found to increase the risk of heart attack and stroke.
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"We found a significant correlation between the degree of inhibition in vitro [in the laboratory] of whole blood cox-2, but not whole blood cox-1," said the report by researchers in Spain and Italy.
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Older NSAIDs, such as ibuprofen and naproxen, act primarily against cox-1.
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A newer generation of NSAIDs that act against cox-2 reduce the gastrointestinal bleeding, pain and inflammation that are major side effects of the cox-1 drugs, but they have been found to increase the risk of heart attack and stroke.
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"We found a significant correlation between the degree of inhibition in vitro [in the laboratory] of whole blood cox-2, but not whole blood cox-1," said the report by researchers in Spain and Italy.
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