Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry An
alicyclic alkyne having eightcarbon atoms in the ring
Etymologies
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Examples
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To apply their copper-free click chemistry to living mice, Bertozzi and her group delivered azides to the surfaces of target cells within the mice via a metabolic precursor, then labeled select glycans (those that bore corresponding azido sialic acids) by covalent reaction in vivo with a panel of cyclooctyne-FLAG peptide conjugates.
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To apply click chemistry to glycans, she and her colleagues designed a ring-shaped molecule, called difluorinated cyclooctyne or DIFO, that reacts with azides rapidly at physiological temperatures without the need for a toxic catalyst.
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To apply click chemistry to glycans, she and her colleagues designed a ring-shaped molecule, called difluorinated cyclooctyne or DIFO, that reacts with azides rapidly at physiological temperatures without the need for a toxic catalyst.
THE MEDICAL NEWS 2010
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To apply their copper-free click chemistry to living mice, Bertozzi and her group delivered azides to the surfaces of target cells within the mice via a metabolic precursor, then labeled select glycans (those that bore corresponding azido sialic acids) by covalent reaction in vivo with a panel of cyclooctyne-FLAG peptide conjugates.
THE MEDICAL NEWS 2010
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