Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An enzyme that catalyzes the removal of hydrogen from a substrate and the transfer of the hydrogen to an acceptor in an oxidation-reduction reaction.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any of several enzymes that catalyze the removal of hydrogen (a proton) from biological compounds.

Etymologies

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Examples

  • The University of Leeds researchers said the compounds work by preventing the enzyme dihydroorotate dehydrogenase, which is essential to the growth of the parasite Plasmodium falciparum, from working.

    Latest News - UPI.com 2009

  • As a result, most patients with glutamate dehydrogenase hyperinsulinism will be responsive to Diazoxide.

    Diazoxide 2010

  • The region includes genes encoding a CoA-dependent methylmalonate semialdehyde dehydrogenase (dntE), a putative NADH-dependent dehydrogenase (ORF13), and a bifunctional isomerase/hydrolase (dntG).

    Casey Luskin on Kitzmiller & Information 2010

  • These steps are catalysed be the enzymes alcohol dehydrogenase and aldehyde dehydrogenase respectively.

    Hangover Cures: Myth, Legend, Fact | Lifehacker Australia 2010

  • First, a few basics: the ailment is known as G6PD deficiency (for glucose-6-phosphate dehydrogenase) and, according to a 2008 article in The Lancet, it "is the most common human enzyme defect, being present in more than 400 million people worldwide."

    Randall Amster: The Most Common Disease You've Never Heard Of Randall Amster 2010

  • Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene.

    Resources for Professionals 2010

  • Stanley CA, Lieu YK, Hsu BY, Burlina AB, Greenberg CR, Hopwood NJ, et al. Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene.

    Resources for Professionals 2010

  • Deficiencies of pyruvate dehydrogenase (PDH) and pyruvate carboxylase (PDH and PC); Leigh syndrome

    Biochemical Genetics-Metabolic Disease 2010

  • Other blood tests (your doctor will determine how often), including chemistries; lactate dehydrogenase; and adrenal hormones such as cortisol, testosterone, 17-hydroxyprogesterone, androstenedione and dehydroepiandrosterone

    Li-Fraumeni Syndrome 2009

  • It has been observed in patients with2,5 and without4,7 glucose-6-phosphate dehydrogenase (G6PD) deficiency and is characterized by the presence of Heinz bodies.

    Phenazopyridine 2010

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