Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
antimalarial drug , the activemetabolite of allartemisinin compounds , also available as a drug in itself.
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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In addition, data show that the currently available dihydroartemisinin preparations fail to meet the internationally accepted stability requirements.
BioMed Central - Latest articles Frans Herwig Jansen 2010
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WHO has now added a fifth ACT - dihydroartemisinin plus piperaquine - to the previous list of recommended medicines.
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However, experimental testing demonstrates that, due to its intrinsic chemical instability, dihydroartemisinin is not suitable to be used in pharmaceutical formulations.
BioMed Central - Latest articles Frans Herwig Jansen 2010
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The pharmaceutical death-ride of dihydroartemisinin
BioMed Central - Latest articles Frans Herwig Jansen 2010
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In the 26 subjects further analyzed, we found no interference with the pharmacokinetics of parenteral AS or its pharmacologically active metabolite dihydroartemisinin. oAC protects against ECM in mice, and does not interfere with the pharmacokinetics of parenteral artesunate.
Elites TV PLoS ONE 2010
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In the 2010 second edition of WHO's guidelines for the treatment of malaria, the relatively new fixed dose combination dihydroartemisinin-piperaquine is included as one of the recommended artemisinin combination therapies.
BioMed Central - Latest articles Frans Herwig Jansen 2010
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Samples were genotyped using both gel and capillary electrophoresis from randomized trials of artemether-lumefantrine (AL) vs. dihydroartemisinin-piperaquine (DP) performed in two areas of Uganda: Kanungu, where transmission is moderate, and Apac, where transmission is very high.
BioMed Central - Latest articles Vinay Gupta 2010
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The results of two new large scale trials show that the combination of dihydroartemisinin and piperaquine (DHA+PQP) not only is effective against uncomplicated malaria in a way which is comparable to other artemisinin-based combination therapies (ACTs), but it also protects patients against new infections for at least two months after treatment.
Emaxhealth 2009
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A dihydroartemisinin-amodiaquine combination was the most used therapy for children under five years of age (29. 0\%, n = 177).
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In addition to the parent compound, a number of artemisinin derivatives are available to treat malaria; these include artesunate, artemether, artemotil, and dihydroartemisinin.
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