Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun cytology The normal state of a
diploid eukaryotic cell or individual which has two members of a pair ofhomologous chromosomes in eachnucleus . Anormal chromosome is representedtwice in a single cell.
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word disomy.
Examples
-
We can also determine parent of origin for deletions and uniparental disomy.
Cytogenomics Lab 2010
-
We can diagnose numerous single gene disorders, both dominant and recessive, as well as cases of uniparental disomy.
Cytogenomics Lab 2010
-
Leinonen R, Lindgren CM, Kivinen K, Dahlman-Wright K, et al. (2005) Global analysis of uniparental disomy using high density genotyping arrays.
PLoS ONE Alerts: New Articles Outi Hovatta et al. 2010
-
Recent advances in genome-wide single-nucleotide polymorphism (SNP) analyses have revealed previously unrecognized microdeletions and uniparental disomy (UPD) in a broad spectrum of human cancers.
Naturejobs - All Jobs L Bullinger 2010
-
The frequencies of different subtypes in PWS are usually given in literature as 70 maternal uniparental disomy (mUPD) and 3-5% others (imprinting centre (IC) defects and translocations).
Naturejobs - All Jobs Margje Sinnema 2010
-
In contrast, PDP-FISH has been reported for three CNV loci using fosmid probes, which distinguish signal presence and absence rather than signal intensity differences pod-FISH has already been successfully used to identify the parental origin of individual derivative chromosomes, such as the characterization of chimerism and uniparental disomy 15
PLoS ONE Alerts: New Articles Hasmik Mkrtchyan et al. 2010
-
Uniparental disomy 7 was excluded for both cell lines and the result was confirmed by microsatellite analysis.
PLoS ONE Alerts: New Articles Hasmik Mkrtchyan et al. 2010
-
Recent advances in genome-wide single-nucleotide polymorphism (SNP) analyses have revealed previously unrecognized microdeletions and uniparental disomy (UPD) in a broad spectrum of human cancers.
Naturejobs - All Jobs L Bullinger 2010
-
The combined measurement of both allelic ratios and normalized intensities provides enhanced detectability of aberrations and allows identification of copy-neutral genetic anomalies, such as uniparental disomy and mitotic recombination.
GEN News Highlights 2009
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.