Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun   Alternative spelling of downregulation .
Etymologies
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Examples
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								Perhaps the lack of response in moss and lichens reflects their adaptation to the currently high levels of CO2 that they experience close to the ground surface [106] via the process of down-regulation. Phenotypic responses of arctic species to changes in climate and ultraviolet-B radiation 2009 
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								The first experiment that manipulated CO2 in the Arctic concluded that elevated CO2 concentrations had no long-term effects because photosynthetic acclimation (i.e., down-regulation, the physiological adjustment of photosynthetic rate so that no differences are found between plants grown at ambient and elevated CO2 levels) in cottongrass ( '' Eriophorum vaginatum '') was apparent within three weeks and biomass did not increase. Phenotypic responses of arctic species to changes in climate and ultraviolet-B radiation 2009 
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								When we quiet the mind, contemplate, and conceive the details of what we desire, this affects the development of neural pathways that promote the down-regulation of the sympathetic nervous system, (read this as 'stress central'), and promotes relaxation, harmony, well-being. 
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								In any case, the goal is to find a target where up- or down-regulation might plausibly be therapeutic, and then to develop a high-throughput assay for that up- or down-regulation. How drugs are made: part I Silas 2008 
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								In any case, the goal is to find a target where up- or down-regulation might plausibly be therapeutic, and then to develop a high-throughput assay for that up- or down-regulation. Archive 2008-07-01 Yttrai 2008 
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								Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIVcpz strains 
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								As such, these cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms neoangiogenesis and down-regulation of inflammation toward tissue and bone repair and regeneration. unknown title 2011 
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								We also identified down-regulation of catalase, which has important antioxidant functions. PLoS ONE Alerts: New Articles Franco Folli et al. 2010 
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								Effects of trehalose injection on expressions of key genes in the chitin biosynthesis pathway In addition to the down-regulation of trehalase expression, an examination of an indirect up-regulation of trehalases by the injection of trehalose was conducted. PLoS ONE Alerts: New Articles Jie Chen et al. 2010 
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								Unlike other RNA therapeutic approaches, AVI's antisense technology has been used to directly target both messenger RNA (mRNA) and its precursor (pre-mRNA), allowing for both up and down-regulation of targeted genes and proteins. 
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