Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics, medicine The ability of a portion of a
genome to be targeted by adrug , especially by a small molecule drug
Etymologies
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Examples
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Potential areas of study for the future are proposed, which include a new classification system consisting of specific families and the identification of PPI targets with high druggability potential based on key descriptors of the interaction.
Elites TV PLoS ONE 2010
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However, it should be noted that this type of analysis represents an initial step, since the druggability of each site requires evaluation by medicinal chemists
PLoS ONE Alerts: New Articles Pierre M. Durand et al. 2008
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Coleman RG, Smyth KT, Cao Q, Soulard P, et al. (2007) Structure-based maximal affinity model predicts small-molecule druggability.
PLoS ONE Alerts: New Articles Pierre M. Durand et al. 2008
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2P2I database stores structural information about PPIs with known inhibitors and provides a useful tool for biologists to assess the potential druggability of their interfaces.
Elites TV PLoS ONE 2010
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