Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A glycoprotein located on the surface of cells

Etymologies

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Examples

  • The drugs act on an enzyme linked to production of these proteins, soluble FLt-1 and soluble endoglin.

    BBC News - Home 2011

  • The other factor, soluble endoglin, is a co-receptor for TGF-β

    Newswise: Latest News 2010

  • The TGF-β pathway controls growth and Gingery proposes that soluble endoglin inhibits cell growth by reducing the signaling of this pathway.

    Newswise: Latest News 2010

  • Gingery studies two factors released during preeclampsia: sFlt-1 and soluble endoglin. sFlt-1 is a soluble version of a protein called VEGF (vascular endothelial growth factor), which regulates the growth of cells.

    Newswise: Latest News 2010

  • Mutations in endoglin and activin-like kinase receptor 1 (ALK1) cause hereditary hemorrhagic telangiectasia, whereas bone morphogenetic protein type II receptor (BMPR-II) mutations underlie familial pulmonary arterial hypertension.

    Journal of Biological Chemistry current issue P. D. Upton 2009

  • However, small interfering RNA and inhibitor studies showed no involvement of ALK5 or endoglin.

    Journal of Biological Chemistry current issue P. D. Upton 2009

  • To do that, they injected mice with a virus that produces large quantities of soluble endoglin, a protein that would circulate, and then bind to and inhibit TGF-beta.

    Latest News from SYS-CON ITALIA 2009

  • Genetic linkage studies identified two genes primarily related to HHT: endoglin (ENG) on chromosome 9q33-34 and activin receptor-like kinase1 (ACVRL1) on chromosome 12q13.

    BioMed Central - Latest articles Haneen Sadick 2009

  • To do that, they injected mice with a virus that produces large quantities of soluble endoglin, a protein that would circulate, and then bind to and inhibit TGF-beta.

    The Earth Times Online Newspaper 2009

  • Ets related gene (ERG) has recently been shown to participate in the transcriptional regulation of a number of endothelial specific genes including VE-cadherin (CD144), endoglin, and von Willebrand's Factor (vWF).

    BioMed Central - Latest articles Vesna Nikolova-Krstevski 2009

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