Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A drug that blocks tumor necrosis factor receptors and is used to treat autoimmune diseases, especially rheumatoid arthritis and psoriasis.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
drug that treatsautoimmune diseases by interfering with the TNFreceptor (part of theimmune system ).
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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The new study documents a dramatic and unprecedented therapeutic effect in an Alzheimer’s patient: improvement within minutes following delivery of perispinal etanercept, which is etanercept given by injection in the spine.
Reversal Of Alzheimer’s Symptoms Within Minutes In Human Study « Isegoria 2008
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Nowadays, with aggressive treatment, including combinations of medications plus the new Biologic therapies (such as etanercept, adalimumab and abatacept), we are able to control the inflammation and prevent joint damage in the majority of patients.
Penn State Live 2010
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• Therapy with TNF antagonists such as etanercept and infliximab is highly active in patients with RA through downmodulation of both synovial inflammation and cartilage and bone destruction.
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The National Institute for Health and Clinical Excellence, or NICE, said in final draft guidance that Simponi will now be an option for treating active and progressive psoriatic arthritis in adults if used in place of the other tumor necrosis factor, or TNF, inhibitor treatments for the illness—etanercept, infliximab and adalimumab.
U.K.' Regulator Backs Merck's Rheumatoid Arthritis Drug Sten Stovall 2011
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Researchers at the Donald W. Reynolds Institute on Aging at the University of Arkansas for Medical Sciences (UAMS) gave an Alzheimer's patient an injection of a compound called perispinal etanercept and noticed a "dramatic and unprecedented therapeutic effect" within minutes of the injection.
Boing Boing 2008
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The study, reported on Sunday in the journal BioMed Central BMC Neurology, involved 12 patients who had greatly improved language recall shortly after treatment with Enbrel, or etanercept, an anti-inflammatory drug co-marketed by Amgen and Wyeth.
Drug restores speech in Alzheimer’s; experts worry « Isegoria 2008
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To reduce elevated TNF, the authors gave patients an injection of an anti-TNF therapeutic called etanercept.
Reversal Of Alzheimer’s Symptoms Within Minutes In Human Study « Isegoria 2008
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Based on that information, the agency issued a black box warning about infections from etanercept (Enbrel), including serious infections leading to hospitalization or death.
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The psoriasis treatment Enbrel etanercept is a well known biologic designed to alter a specific aspect of human the immune system — TNF-receptors.
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One of the main differences between Enbrel and Humira is how they were created: Enbrel (etanercept) was created by fusing a protein and a human gene together while Humira (adalimumab) is made entirely from a human monoclonal antibody (as opposed to treated animal cells).
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