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Examples
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Diclofenac almost tripled the risk, while etoricoxib and diclofenac were associated with around a fourfold increased risk of suffering death from cardiovascular causes.
High doses of common painkillers increase stroke risk, warn researchers 2011
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Therefore, etoricoxib offers no unique benefits but carries a risk not associated with older pain relievers.
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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In randomized trials, etoricoxib was associated with increased cardiac risks when compared to naproxen.
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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Arcoxia, whose generic name is etoricoxib, is a COX-2 inhibitor – a kind of painkiller once touted as a miracle cure for osteoarthritis because it was supposed to be easier on the stomach.
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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Wolfe pointed out that trial data presented by Merck on cardiovascular risks compared etoricoxib with diclofenac, which is much more cardio-toxic than older, safer pain relievers.
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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Further, with regards to serious gastrointestinal problems, there is no evidence of benefits of taking etoricoxib compared to diclofenac, a non-steroidal anti-inflammatory drug.
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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“How can the approval of etoricoxib and the large numbers of preventable, life-threatening cardiovascular adverse reactions be justified?”
FDA Should Not Approve Painkiller Dubbed "Offspring of Vioxx" 2007
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The risk of first heart attack varied widely with celecoxib (Celebrex ®) having the lowest at an increased risk of 6% and etoricoxib (Arcoxia®) having a huge increased risk of 121%.
NSAIDs (Advil, Aleve, Vioxx...) increases risk of first heart attack 2006
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The risk of first heart attack varied widely with celecoxib (Celebrex ®) having the lowest at an increased risk of 6% and etoricoxib (Arcoxia®) having a huge increased risk of 121%. '
NSAIDs (Advil, Aleve, Vioxx...) increases risk of first heart attack 2006
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By inference, he argues etoricoxib must also increase c-v risk.
Archive 2006-10-01 james gaulte 2006
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