Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or pertaining to
exocytosis
Etymologies
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Examples
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Zonta M, Pozzan T, Vicini S, Carmignoto G (2001) Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate.
PLoS Biology: New Articles Marta Gómez-Gonzalo et al. 2010
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UDP-sugar release includes an exocytotic component.
Journal of Biological Chemistry current issue J. I. Sesma 2009
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Here, we provide the first evidence for increased autophagy and increased exocytotic activity in the aged RPE and the presence of autophagy and exosome markers in drusen of AMD patients.
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Although we have not studied any one process in detail, our findings link aspects of aging, oxidative stress, mtDNA damage, autophagy, lysosomal activity, exocytotic activity as functional processes of RPE that have changed in the aged eye.
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We provide the first evidence for an apparent increased exocytotic activity in the aging RPE.
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Intracellular overload of damaged macromolecules leads to increased exocytotic activity.
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We hypothesized that RPE cells with decreased lysosomal activity and increased exocytotic activity will release signals for recruitment of leukocytes, particularly macrophages, to aid in the digestion of extracellular deposits.
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We hypothesized that compromised RPE will remove damaged intracellular macromolecules without completely digesting them by increasing exocytotic activity.
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We then asked whether we could find evidence for increased exocytotic activity in the RPE / choroid with age.
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[3], [31] and the intracellular proteins that are found in exosomes Comparison, from the literature, of exosome proteome and drusen proteome We hypothesize that, in the aged RPE in vivo, there is age-related, increased exocytotic activity lead to the release of intracellular proteins via exosomes which contribute to the formation of drusen.
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