Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A mycotoxin, originally isolated from Gliocladium fimbriatum, that causes apoptosis of certain cells

Etymologies

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Examples

  • Krauss B, Schulze-Osthoff K, Decker T, Traenckner EB, et al. (1996) The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

    PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010

  • Stanzani M, Orciuolo E, Lewis R, Kontoyiannis DP, Martins SL, et al. (2005) Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes.

    PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010

  • Orciuolo E, Stanzani M, Canestraro M, Galimberti S, Carulli G, et al. (2007) Effects of Aspergillus fumigatus gliotoxin and methylprednisolone on human neutrophils: implications for the pathogenesis of invasive aspergillosis.

    PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010

  • Hyphal extracts contain gliotoxin, an immunosuppressive mycotoxin, which induces apoptosis of antigen-presenting cells and inhibits transcription factor NF-κB

    PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010

  • (Velcade (R)), gliotoxin, PR11 and PR39 were tested and compared to chloroquine - and artesunate-activities in a standardized in vitro drug susceptibility assay against P. falciparum laboratory strains 3D7, D10 and Dd2.

    BioMed Central - Latest articles Peter G Kremsner and Benjamin Andrea Kreidenweiss 2008

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