Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry An
enzyme that is needed tocleave , byhydrolysis , the beta-glucosidic linkage ofglucocerebroside , anintermediate inglycolipid metabolism , andmutations in which causeGaucher's disease .
Etymologies
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Examples
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For example, people with Gaucher disease are deficient in the enzyme glucocerebrosidase, which is responsible for breaking down a certain fat molecule called glucocerebroside.
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For example, people with Gaucher disease are deficient in the enzyme glucocerebrosidase, which is responsible for breaking down a certain fat molecule called glucocerebroside.
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Currently, several biotechnology companies have used plant biotechnology to produce protein pharmaceuticals, such as glucocerebrosidase to treat Gaucher disease in our case, lipase to treat cystic fibrosis, alpha-interferon, lactoferrin, and others, which are under evaluation in human studies
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Taliglucerase alfa, the Company's proprietary plant-cell expressed form of glucocerebrosidase GCD, is in development for the treatment of Gaucher disease.
unknown title 2011
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The accumulation of glucocerebrosidase in the liver and spleen leads to organomegaly.
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The company's lead product is recombinant glucocerebrosidase, a treatment for Gaucher disease-a rare genetic disorder caused by a deficiency of the enzyme that breaks down fatty substances.
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Thomas Goetz illustrates the utility of the 23andMe approach with a simple example: a massive study of the association between glucocerebrosidase mutations and Parkinson's disease published late last year, the key finding of which was successfully replicated by analysis done by 23andMe on their
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In June 2009, Genzyme temporarily halted production of their modified glucocerebrosidase, Cerezyme, produced in mammalian cell cultures, due to viral contamination.
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The disorder is caused by lack of an enzyme called glucocerebrosidase.
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GBA gene which results in a deficiency of the lysosomal enzyme beta-glucocerebrosidase.
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