Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
sympatholytic drug .
Etymologies
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Examples
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The drug is called guanfacine and clinical trials are underway at Yale University in Connecticut to confirm its beneficial effect in enhancing so-called working memory in older adults.
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Researchers from Yale University in America are already recruiting human subjects for a clinical trial to determine whether guanfacine, which is already used to treat hypertension in adults, can improve working memory in elderly people.
Telegraph.co.uk - Telegraph online, Daily Telegraph and Sunday Telegraph 2011
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Researchers from Yale University in America are already recruiting human subjects for a clinical trial to determine whether guanfacine, which is already used to treat hypertension in adults, can improve working memory in elderly people.
Telegraph.co.uk - Telegraph online, Daily Telegraph and Sunday Telegraph 2011
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Causes of memory declineResearchers have linked declines in working memory to the accumulation of a protein called cyclic-AMP in the prefrontal cortex, but guanfacine reduced the protein to more youthful levels.
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Arnsten says researchers then gave the older animals the blood pressure drug guanfacine and the differences in neuronal firing between the older and younger primates narrowed.
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Arnsten developed a long-acting version of guanfacine for children with attention deficit hyperactivity disorder and she collects royalties.
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Arnsten hopes that delays in working memory in older adults, frequently referred to as “senior moments,” may one day be treated with small doses of guanfacine.
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An article on working-memory improvements obtained with the drug guanfacine is published in the journal Nature.
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Nature, scientists found that by using the drug guanfacine, they were able to lower levels of a brain chemical called cAMP cyclic adenosine monophosphate to strengthen the
The Full Feed from HuffingtonPost.com The Huffington Post News Editors 2011
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Drugs which block the production of cAMP, including guanfacine, restored the nerve cells' rate of firing to a level seen in young adult monkeys.
Telegraph.co.uk - Telegraph online, Daily Telegraph and Sunday Telegraph 2011
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