Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
oligomer having sevensubunits
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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After endocytosis, at low pH, the heptamer dissociates from the receptors and inserts into the lipid bilayer forming a pore through which partially unfolded EF and LF cross the membrane
PLoS ONE Alerts: New Articles Andrea Puhar et al. 2008
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On to the cell surface, PA forms a heptamer that binds up to three molecules of EF or LF
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After endocytosis, at low pH, the heptamer dissociates from the receptors and inserts into the lipid bilayer forming a pore through which partially unfolded EF and LF cross the membrane
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After endocytosis, at low pH, the heptamer dissociates from the receptors and inserts into the lipid bilayer forming a pore through which partially unfolded EF and LF cross the membrane
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This could be due to its putative mechanism of action compared to other monoclonal candidates under development - binding to protective antigen and inhibiting heptamer (pore) formation, rather than inhibiting binding of toxin to its receptor.
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